DDIT4L antibody (AA 2-98) (PE)
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- Target See all DDIT4L Antibodies
- DDIT4L (DNA-Damage-Inducible Transcript 4-Like (DDIT4L))
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Binding Specificity
- AA 2-98
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This DDIT4L antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Specificity
- The mouse monoclonal antibody DDIT-03 recognizes DDIT4L / REDD2 protein, which belongs to intracellular stress-induced proteins involved in mediation of cell death.
- Cross-Reactivity (Details)
- Human
- Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- N-terminal recombinant fragment of human DDIT4L (amino acids 2-98)
- Clone
- DDIT-03
- Isotype
- IgG1
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- Application Notes
- Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.
- Comment
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate was purified by size-exclusion chromatography.
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Target
- DDIT4L (DNA-Damage-Inducible Transcript 4-Like (DDIT4L))
- Alternative Name
- DDIT4L (DDIT4L Products)
- Synonyms
- 1700037B15Rik antibody, 1700108M02Rik antibody, REDD2 antibody, RTP801L antibody, Smhs1 antibody, Rtp801L antibody, DNA-damage-inducible transcript 4-like antibody, DNA damage inducible transcript 4 like antibody, Ddit4l antibody, DDIT4L antibody, ddit4l antibody
- Background
- DNA damage inducible transcript 4 like,DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.,DDIT4L, REDD2, Rtp801L
- Gene ID
- 115265
- UniProt
- Q96D03
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