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SIGLEC7 antibody

SIGLEC7 Reactivity: Human FACS Host: Mouse Monoclonal 6-434 unconjugated
Catalog No. ABIN2749061
  • Target See all SIGLEC7 Antibodies
    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
    Reactivity
    • 83
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 63
    • 20
    Mouse
    Clonality
    • 63
    • 19
    • 1
    Monoclonal
    Conjugate
    • 37
    • 12
    • 10
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIGLEC7 antibody is un-conjugated
    Application
    • 61
    • 44
    • 40
    • 15
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    The mouse monoclonal antibody 6-434 recognizes an extracellular epitope of CD328 (Siglec-7), a 75 kDa transmembrane glycoprotein expressed mainly on NK cells, dendritic cells and monocytes.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    human dendritic cells
    Clone
    6-434
    Isotype
    IgG1
    Top Product
    Discover our top product SIGLEC7 Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
    Alternative Name
    CD328 / Siglec-7 (SIGLEC7 Products)
    Synonyms
    SIGLEC7 antibody, AIRM1 antibody, CD328 antibody, CDw328 antibody, D-siglec antibody, QA79 antibody, SIGLEC-7 antibody, SIGLEC19P antibody, SIGLECP2 antibody, p75 antibody, p75/AIRM1 antibody, sialic acid-binding Ig-like lectin 7 antibody, sialic acid binding Ig like lectin 7 antibody, LOC468976 antibody, SIGLEC7 antibody
    Background
    Sialic acid binding Ig like lectin 7,CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells.,SIGLEC7, p75/AIRM1, D-siglec
    Gene ID
    27036
    UniProt
    Q9Y286
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