BST1 antibody

Catalog No. ABIN2749045

Product Details anti-BST1 Antibody

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This BST1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: The mouse monoclonal antibody SY11B5 recognizes CD157, an approximately 45 kDa GPI-anchored extracellular protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells.

Cross-Reactivity (Details): Human, Non-Human Primates

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: Human CD157

Clone: SY11B5

Isotype: IgG1 kappa

Application Details

Application Notes: Western blotting: Non-reducing conditions.
Immunohistochemistry: Recommended dilution: 5-10 μg/mL.
Flow cytometry: Recommended dilution: 1-12 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for BST1

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Alternative Name: CD157 (BST1 Products)

Synonyms: BST1 antibody, 114/A10 antibody, A530073F09 antibody, BP-3 antibody, Bp3 antibody, Bsta1 antibody, CD157 antibody, Ly65 antibody, bone marrow stromal cell antigen 1 antibody, BST1 antibody, Bst1 antibody

Background: Bone marrow stromal cell antigen 1,CD157 (cADPr hydrolase 2) is a GPI-anchored ectoenzyme possessing ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activity. It uses NAD and cADP-ribose as substrates. CD157 is expressed on granulocytes, monocytes, macrophages, follicular dendritic cells, bone marrow stromal cells and human umbilical cord vein endothelial cells. In case of rheumatoid arthritis is expression is often higher and it is also differentially expressed in the myeloid leukemias. It may also have a signaling role.,BST1, cADPr hydrolase 2

Gene ID: 683

UniProt: Q10588