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CD2 antibody

CD2 Reactivity: Human FACS, Func Host: Mouse Monoclonal TS1-8 unconjugated
Catalog No. ABIN2749021
  • Target See all CD2 Antibodies
    CD2
    Reactivity
    • 156
    • 37
    • 18
    • 15
    • 12
    • 10
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 127
    • 44
    • 24
    • 1
    Mouse
    Clonality
    • 151
    • 43
    • 2
    Monoclonal
    Conjugate
    • 85
    • 23
    • 21
    • 17
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD2 antibody is un-conjugated
    Application
    • 140
    • 51
    • 50
    • 34
    • 34
    • 32
    • 19
    • 13
    • 11
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Specificity
    The mouse monoclonal antibody TS1/8 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Endotoxin Level
    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    Immunogen
    Cytotoxic T lymphocytes
    Clone
    TS1-8
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD2 Primary Antibody
  • Application Notes
    Functional application: Blocking.
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4
    Preservative
    Azide free
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Zhang, Dai, Li, Zhuang: "Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." in: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).

  • Target
    CD2
    Alternative Name
    CD2 (CD2 Products)
    Synonyms
    CD2 antibody, LFA-2 antibody, Ly-37 antibody, Ly37 antibody, SRBC antibody, T11 antibody, CD2R antibody, LFA2 antibody, OX-34 antibody, OX34 antibody, CD2 molecule antibody, CD2 antigen antibody, Cd2 molecule antibody, CD2 antibody, Cd2 antibody
    Background
    CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
    Gene ID
    914
    UniProt
    P06729
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