CD2 antibody
(1 reference)-
- Target See all CD2 Antibodies
- CD2
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD2 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Specificity
- The mouse monoclonal antibody TS1/8 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.
- Cross-Reactivity (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Purity
- > 95 % (by SDS-PAGE)
- Endotoxin Level
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
- Immunogen
- Cytotoxic T lymphocytes
- Clone
- TS1-8
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD2 Primary Antibody
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anti-CD2 (CD2) (AA 25-140) antibody
CD2 Reactivity: Human FACS, WB, ELISA, IHC Host: Mouse Monoclonal 3D1E3 unconjugated
anti-CD2 (CD2) (AA 25-140) antibodyCD2 Reactivity: Human FACS, WB, ELISA, IHC Host: Mouse Monoclonal 3D1B4 unconjugated
anti-CD2 (CD2) (N-Term) antibodyCD2 Reactivity: Human WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-CD2 (CD2) antibody (FITC)CD2 Reactivity: Human FACS Host: Mouse Monoclonal LT2 FITC
anti-CD2 (CD2) antibody (PE)CD2 Reactivity: Human FACS Host: Mouse Monoclonal LT2 PE
anti-CD2 (CD2) (AA 1-351) antibodyCD2 Reactivity: Human WB, IHC (p) Host: Mouse Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 Reactivity: Human FACS, IF, WB, Func Host: Mouse Monoclonal 1E7E8-G4 unconjugated
anti-CD2 (CD2) (AA 25-209) antibodyCD2 Reactivity: Human IF, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-65 unconjugated
anti-CD2 (CD2) antibodyCD2 Reactivity: Human FACS, IP Host: Mouse Monoclonal LT2 unconjugated
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- Application Notes
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Functional application: Blocking.
Flow cytometry: Recommended dilution: 1-4 μg/mL - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4
- Preservative
- Azide free
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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: "Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." in: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).
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: "Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." in: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).
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- Target
- CD2
- Alternative Name
- CD2 (CD2 Products)
- Synonyms
- CD2 antibody, LFA-2 antibody, Ly-37 antibody, Ly37 antibody, SRBC antibody, T11 antibody, CD2R antibody, LFA2 antibody, OX-34 antibody, OX34 antibody, CD2 molecule antibody, CD2 antigen antibody, Cd2 molecule antibody, CD2 antibody, Cd2 antibody
- Background
- CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
- Gene ID
- 914
- UniProt
- P06729
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