Retinol-Binding Protein antibody

Catalog No. ABIN2743999

Product Details anti-Retinol-Binding Protein Antibody

Target: Retinol-Binding Protein (RBP)

Reactivity: Human, Mouse, Goat, Monkey, Rat, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinol-Binding Protein antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Specificity: Human RBP / Retinol Binding Protein

Purification: Protein G purified

Immunogen: Retinol binding protein purified from human plasma.

Type of Immunogen: Purified protein

Clone: G4E4

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ELISA, IF (1 - 2 μg/mL), IHC, IHC-Fr (1 - 2 μg/mL), IHC-P (1 - 2 μg/mL), IP, WB (0.5 - 1 μg/mL)

Usage: This antibody recognizes a protein of 21  kDa-25  kDa, identified as retinol binding protein (RBP). Its epitope localizes between amino acids 74-182. The RBP antibody recognizes reduced and carboxy-methylated RBP as well as the circulatory RBP but not the native form, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). Retinol binding protein is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism. ELISA: Order BSA-free antibody format for coating.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C to 8°C.

Target Details for Retinol-Binding Protein

Target: Retinol-Binding Protein (RBP)

Alternative Name: RBP / Retinol Binding Protein (RBP Products)

Background: Name/Gene ID: RBP

Synonyms: RBP