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EBNA antibody

EBNA Reactivity: Epstein-Barr Virus (EBV) IHC (fro), IP, IHC, WB, IF Host: Mouse Monoclonal 1108-1 unconjugated
Catalog No. ABIN2740459
  • Target See all EBNA products
    EBNA (Epstein-Barr Virus Nuclear Antigen (EBNA))
    Reactivity
    Epstein-Barr Virus (EBV)
    Host
    • 2
    • 1
    Mouse
    Clonality
    • 2
    • 1
    Monoclonal
    Conjugate
    • 3
    This EBNA antibody is un-conjugated
    Application
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
    Specificity
    Human EBV Early Nuclear Antigen
    Purification
    Protein G purified
    Immunogen
    Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt's lymphoma sera.

    Type of Immunogen: Cells
    Clone
    1108-1
    Isotype
    IgG1 kappa
  • Application Notes
    Approved: IF (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

    Usage: Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (EaD) and restricted (EaR) components. The activity of EaD is suppressed during latent infection. BMRF1, the gene that encodes for EaD, is closely associated with the gene encoding for EBV DNA polymerase, and EaD is essential for the activity of this polymerase. EaD forms a complex with EBV DNase and, together, they may play a role in viral replication.
    Comment

    Target Species of Antibody: Epstein-Barr Virus

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2°C to 8°C.
  • Target
    EBNA (Epstein-Barr Virus Nuclear Antigen (EBNA))
    Alternative Name
    EBV Early Nuclear Antigen (EBNA Products)
    Target Type
    Viral Protein
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