RUNX1T1 antibody
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- Target See all RUNX1T1 Antibodies
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This RUNX1T1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Characteristics
- Homo sapiens runt-related transcription factor 1, translocated to, 1 (cyclin D-related) (RUNX1T1), transcript variant 3
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human RUNX1T1(NP_783553) produced in HEK293T cell.
- Clone
- 1H1
- Isotype
- IgG1
- Top Product
- Discover our top product RUNX1T1 Primary Antibody
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- Application Notes
- WB 1:2000, IF 1:100,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
- Alternative Name
- RUNX1T1 (RUNX1T1 Products)
- Synonyms
- MTG8 antibody, si:ch211-232j17.1 antibody, wu:fi14b07 antibody, zgc:154044 antibody, AML1T1 antibody, CBFA2T1 antibody, CDR antibody, ETO antibody, ZMYND2 antibody, Cbfa2t1h antibody, Cbfa2t1 antibody, runt-related transcription factor 1; translocated to, 1 (cyclin D-related) antibody, RUNX1 translocation partner 1 L homeolog antibody, RUNX1 translocation partner 1 antibody, runx1t1 antibody, runx1t1.L antibody, RUNX1T1 antibody, Runx1t1 antibody
- Background
- This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 63 kDa
- Gene ID
- 862
- NCBI Accession
- NM_175635
- HGNC
- 862
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