PBX1 antibody
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- Target See all PBX1 Antibodies
- PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PBX1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Characteristics
- Homo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human PBX1(NP_002576) produced in HEK293 cell.
- Clone
- 1C11
- Isotype
- IgG1
- Top Product
- Discover our top product PBX1 Primary Antibody
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- Application Notes
- WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
- Alternative Name
- PBX1 (PBX1 Products)
- Synonyms
- fi29e01 antibody, pbx1b antibody, wu:fi29e01 antibody, zgc:55265 antibody, 2310056B04Rik antibody, AI848790 antibody, AU015730 antibody, D230003C07Rik antibody, Pbx-1 antibody, Pbx1a antibody, Pbx1b antibody, PBX1A antibody, Xpbx1 antibody, Xpbx1b antibody, PBX homeobox 1 antibody, pre-B-cell leukemia homeobox 1a antibody, pre B cell leukemia homeobox 1 antibody, pre-B-cell leukemia homeobox 1 S homeolog antibody, PBX1 antibody, pbx1a antibody, Pbx1 antibody, pbx1.S antibody
- Background
- This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1,19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 46.4 kDa
- Gene ID
- 5087
- NCBI Accession
- NM_002585
- HGNC
- 5087
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