LOX antibody (AA 22-168)
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- Target See all LOX Antibodies
- LOX (Lysyl Oxidase (LOX))
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Binding Specificity
- AA 22-168
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This LOX antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- Characteristics
- Homo sapiens lysyl oxidase (LOX), transcript variant 1
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cell.
- Clone
- 10D11
- Isotype
- IgG1
- Top Product
- Discover our top product LOX Primary Antibody
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- Application Notes
- WB 1:1000, IHC 1:150, IF 1:100, FLOW 1:100,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- LOX (Lysyl Oxidase (LOX))
- Alternative Name
- LOX (LOX Products)
- Synonyms
- LOX antibody, Xlox antibody, MGC146507 antibody, lox antibody, zgc:77447 antibody, AI893619 antibody, TSC-160 antibody, H-rev142 antibody, Rrg1 antibody, lysyl oxidase antibody, lysyl oxidase a antibody, lysyl oxidase L homeolog antibody, LOX antibody, lox antibody, loxa antibody, lox.L antibody, Lox antibody
- Background
- The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 46.8 kDa
- Gene ID
- 4015
- NCBI Accession
- NM_002317
- HGNC
- 4015
- Pathways
- SARS-CoV-2 Protein Interactome
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