GCKR antibody
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- Target See all GCKR Antibodies
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GCKR antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Homo sapiens glucokinase (hexokinase 4) regulator (GCKR)
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human GCKR (NP_001477) produced in HEK293T cell.
- Clone
- 1E7
- Isotype
- IgG1
- Top Product
- Discover our top product GCKR Primary Antibody
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- Application Notes
- WB 1:2000, IHC 1:150, IF 1:100,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
- Alternative Name
- GCKR (GCKR Products)
- Synonyms
- FGQTL5 antibody, GKRP antibody, GLRE antibody, gckr antibody, glucokinase regulator antibody, glucokinase regulatory protein antibody, glucokinase regulator L homeolog antibody, GCKR antibody, Gckr antibody, gckr.L antibody
- Background
- This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
- Molecular Weight
- 68.5 kDa
- Gene ID
- 2646
- NCBI Accession
- NP_001477
- HGNC
- 2646
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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