ETS1 antibody
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- Target See all ETS1 Antibodies
- ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ETS1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects endogenous levels of ETS1 protein. (region surrounding Ala32)
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Purity
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product ETS1 Primary Antibody
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- Application Notes
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ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- DO NOT FREEZE!
- Storage
- 4 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C.
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- Target
- ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))
- Alternative Name
- ETS1 (ETS1 Products)
- Synonyms
- ETS-1 antibody, EWSR2 antibody, ets1a-a antibody, XE1-a antibody, X1-c-ets-1a antibody, ETS-1A antibody, ETS-1B antibody, TNIP1 antibody, c-ets-1 antibody, c-ets1 antibody, Ets-1 antibody, Etsoncb antibody, Tpl1 antibody, ets1 antibody, ets antibody, AI196000 antibody, AI448617 antibody, D230050P06 antibody, cb516 antibody, id:ibd1116 antibody, zgc:110573 antibody, XE1-b antibody, ets-1 antibody, ets1-B antibody, ETS proto-oncogene 1, transcription factor antibody, v-ets avian erythroblastosis virus E26 oncogene homolog 1 S homeolog antibody, v-ets avian erythroblastosis virus E26 oncogene homolog 1 antibody, v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) antibody, E26 avian leukemia oncogene 1, 5' domain antibody, v-ets avian erythroblastosis virus E26 oncogene homolog 1 L homeolog antibody, ETS1 antibody, ets1.S antibody, Ets1 antibody, ets1 antibody, ets1.L antibody
- Background
- Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1-3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element. Evidence indicates that the DNA binding activity by Ets-1 is regulated at the level of phosphorylation.Synonyms: EWSR2, Protein C-ets-1, p54
- Molecular Weight
- approx. 54 kDa
- Gene ID
- 2113
- NCBI Accession
- NP_005229
- UniProt
- P14921
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