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p53 antibody

GMP Grade TP53 Reactivity: Human WB Host: Mouse Monoclonal PAB122 unconjugated
Catalog No. ABIN2704417
  • Target See all p53 (TP53) Antibodies
    p53 (TP53) (Tumor Protein P53 (TP53))
    Reactivity
    • 852
    • 256
    • 213
    • 113
    • 47
    • 34
    • 31
    • 18
    • 10
    • 9
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 648
    • 220
    • 6
    • 2
    • 1
    Mouse
    Clonality
    • 602
    • 274
    • 1
    Monoclonal
    Conjugate
    • 480
    • 43
    • 38
    • 25
    • 21
    • 14
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 12
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This p53 antibody is un-conjugated
    Application
    • 692
    • 334
    • 246
    • 218
    • 192
    • 145
    • 124
    • 119
    • 119
    • 64
    • 54
    • 32
    • 18
    • 17
    • 13
    • 13
    • 12
    • 9
    • 9
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    Anti-p53 Unconjugated Antibody
    Characteristics
    p53, a DNA-binding, oligomerization domain- and transcription activation domaincontaining tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes in the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through post-translational modifications, including phosphorylation and acetylation.
    Purification
    Purified
    Purity
    >95 %
    Grade
    GMP Grade
    Immunogen
    SV40-transformed, 3T3 clone 4 mouse cells
    Clone
    PAB122
    Isotype
    IgG2b, kappa
    Top Product
    Discover our top product TP53 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    p53 (TP53) (Tumor Protein P53 (TP53))
    Alternative Name
    p53 (TP53 Products)
    Synonyms
    BCC7 antibody, LFS1 antibody, P53 antibody, TRP53 antibody, p53 antibody, Trp53 antibody, brp53 antibody, drp53 antibody, etID22686.5 antibody, fb40d06 antibody, wu:fb40d06 antibody, zgc:111919 antibody, Tp53 antibody, bbl antibody, bfy antibody, bhy antibody, p44 antibody, tp53 antibody, Xp53 antibody, TP53 antibody, tumor protein p53 antibody, cellular tumor antigen p53 antibody, transformation related protein 53 antibody, tumor protein p53 L homeolog antibody, TP53 antibody, CpipJ_CPIJ002758 antibody, Tp53 antibody, tp53 antibody, Trp53 antibody, tp53.L antibody
    NCBI Accession
    NM_000546
    UniProt
    P04637
    Pathways
    p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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