Transferrin Receptor antibody (FITC)

Catalog No. ABIN2704332

Product Details anti-Transferrin Receptor Antibody (FITC)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Purpose: CD71 FITC Antibody

Characteristics: The antibody is directed against the transferrin receptor (CD71), the 95 kDa, type II membrane glycoprotein. CD71is expressed on activated, but not resting lymphocytes, monocytes, macrophages, most dividing cells and on brain endothelium, and is upregulated during response to antigens and/or mitogens. The transferrin receptor binds Fe(Apo)-transferrin and via endocytosis and delivers iron required by the growing cell for cellular metabolism.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: Human acute lymphoblastic leukaemia cells

Clone: OKT9

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: CD71 (TFRC Products)

Gene ID: 7073

NCBI Accession: XM_011513112, NM_003234, NM_001128148

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis