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AIM2 antibody (AA 255-354) (PE)

Name: AIM2 antibody (AA 255-354) (PE)
SKU: ABIN2690017
Price: 479.69 USD
Availability: InStock

AIM2 Reactivity: Human, Mouse, Rat WB, FACS Host: Rabbit Polyclonal PE

Image was kindly submitted by a researcher at Duke University Medical Center. (AIM2 antibody (AA 255-354) (PE))

FACS

1 image

Catalog No. ABIN2690017

Datasheet as PDF

Target See all AIM2 Antibodies

AIM2 (Absent in Melanoma 2 (AIM2))
Binding Specificity
15

11

8

7

5

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 255-354
Reactivity
72

24

18

3

3

1
Human, Mouse, Rat
Host
60

11

2
Rabbit
Compatible Secondaries
Clonality
65

8
Polyclonal
Conjugate
37

6

5

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This AIM2 antibody is conjugated to PE
Application
61

33

31

22

13

13

11

9

6

5

3

2

2

1
Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity

Human, Mouse, Rat

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from mouse AIM2

Isotype

IgG

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anti-Absent in Melanoma 2 (AIM2) (AA 1-195) antibody
AIM2 Reactivity: Human ELISA, FACS, ICC Host: Mouse Monoclonal 3C4G11 unconjugated

anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibody
AIM2 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated

anti-Absent in Melanoma 2 (AIM2) (AA 1-50) antibody
AIM2 Reactivity: Human WB, ELISA, IF, FACS Host: Rabbit Polyclonal unconjugated

anti-Absent in Melanoma 2 (AIM2) (AA 81-326) antibody
AIM2 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Absent in Melanoma 2 (AIM2) (Internal Region) antibody
AIM2 Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Absent in Melanoma 2 (AIM2) (AA 4-32), (N-Term) antibody
AIM2 Reactivity: Human WB, IF, FACS Host: Rabbit Polyclonal RB23659 unconjugated

anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibody
AIM2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibody
AIM2 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated

anti-Absent in Melanoma 2 (AIM2) (AA 1-260) antibody
AIM2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

anti-Absent in Melanoma 2 (AIM2) (AA 14-215) antibody
AIM2 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

Application Notes

FCM 1:20-100

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date

12 months
Target

AIM2 (Absent in Melanoma 2 (AIM2))

Alternative Name

AIM2 (AIM2 Products)

Synonyms

AIM2 antibody, PYHIN4 antibody, Gm1313 antibody, Ifi210 antibody, absent in melanoma 2 antibody, AIM2 antibody, Aim2 antibody

Background

Synonyms: Gm1313, Ifi210, Interferon-inducible protein AIM2, Interferon-inducible protein 210, Ifi-210, Interferon-inducible protein p210, Aim2
Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.

Gene ID

383619

UniProt

Q91VJ1

Pathways

Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome