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VWF antibody
VWF
Reactivity: Human
IHC (fro)
Host: Mouse
Monoclonal
2F2
unconjugated
Product Details anti-VWF Antibody
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Target
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VWF
(Von Willebrand Factor (VWF))
Reactivity
All reactivities for VWF antibodies
Human
Host
All hosts for VWF antibodies
Mouse
Clonality
All clonalities for VWF antibodies
Monoclonal
Conjugate
All conjugates for VWF antibodies
This VWF antibody is un-conjugated
Application
All applications for VWF antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro))
Brand
BD Pharmingen™
Characteristics
Reacts with von Willebrand Factor (vWF), a multimeric plasma glycoprotein synthesized by endothelial cells and megakaryocytes. In plasma, vWF circulates as multimers which range from dimers of about 500 kDa to multimers of 20000 kDa. It functions as a carrier for Factor VIII and is a mediator of initial platelet adhesion to subendothelium and platelet-platelet interaction. Platelets bind to vWF through the platelet GPIb/IX (CD42b/CD42a) and GPIIb/IIIa (CD41/CD61) complexes This antibody is effective in detecting vWF by ELISA, with no evidence of cross reactivity with fibronectin or fibrinogen. BD Pharmingen™ Purified Mouse Anti-Human vWF - Purified - Clone 2F2-A9 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.5 mg
Purification
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Clone
2F2
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store undiluted at 4°C.
References for anti-VWF antibody (ABIN2689964)
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Sadler : "von Willebrand factor. " in: The Journal of biological chemistry , Vol. 266 , Issue 34 , pp. 22777-80 , (1992 ) (PubMed ).
Target Details for VWF
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Target
VWF
(Von Willebrand Factor (VWF))
Alternative Name
vWF (VWF Products )
Synonyms
VWF antibody, si:ch1073-474e24.1 antibody, F8VWF antibody, VWD antibody, 6820430P06Rik antibody, AI551257 antibody, B130011O06Rik antibody, C630030D09 antibody, von Willebrand factor antibody, Von Willebrand factor antibody, VWF antibody, vwf antibody, Vwf antibody
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