RT1-BB antibody (Biotin)
RT1-BB
Reactivity: Rat, Mouse
FACS
Host: Mouse
Monoclonal
OX
Biotin
(9 references)-
- Target See all RT1-BB Antibodies
- RT1-BB (RT1 Class II, Locus Bb (RT1-BB))
- Reactivity
- Rat, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This RT1-BB antibody is conjugated to Biotin
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Application
- Flow Cytometry (FACS)
- Brand
- BD Pharmingen™
- Characteristics
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The OX-6 antibody reacts with non-polymorphic determinants of the Rat MHC class II antigen, I-A equivalent. RT1B is found on peripheral B lymphocytes, thymic cortical epithelial and medullary reticular cells, small intestinal villus epithelium, epidermal Langerhans cells, dendritic cells, some tissue macrophage populations, peritoneal mast cells, and a subset of thymocytes, but not on peripheral T cells, erythrocytes, or microglia. The OX-6 mAb cross-reacts with mouse I-A[k] and I-A[s] alloantigens and with a major subset of splenocytes from NOD (I-A[g7]) mice. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.
BD Pharmingen™ Biotin Mouse Anti-Rat RT1B - Biotin - Clone OX-6 - Isotype Mouse IgG1, κ - Reactivity Rat, Ms - 0.5 mg - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Immunogen
- Ia-like Glycoproteins from Wistar Thymocytes
- Clone
- OX
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product RT1-BB Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "Costimulatory molecules CD80 and CD86 in the rat; tissue distribution and expression by antigen-presenting cells." in: Journal of leukocyte biology, Vol. 64, Issue 6, pp. 803-9, (1998) (PubMed).
: "In vitro characterization of rat bone marrow-derived dendritic cells and their precursors." in: Journal of leukocyte biology, Vol. 59, Issue 2, pp. 196-207, (1996) (PubMed).
: "Flow cytometric identification of a minority population of MHC class II positive cells in the normal rat retina distinct from CD45lowCD11b/c+CD4low parenchymal microglia." in: The British journal of ophthalmology, Vol. 79, Issue 9, pp. 834-40, (1996) (PubMed).
: "Rat peritoneal mast cells present antigen to a PPD-specific T cell line." in: Cellular immunology, Vol. 158, Issue 1, pp. 253-64, (1994) (PubMed).
: "Modulation of MHC class II determinants on rat Langerhans cells during short term culture." in: Advances in experimental medicine and biology, Vol. 329, pp. 29-34, (1993) (PubMed).
: "Accessory cells of the lung. II. Ia+ pulmonary dendritic cells display cell surface antigen heterogeneity." in: American journal of respiratory cell and molecular biology, Vol. 5, Issue 3, pp. 276-83, (1991) (PubMed).
: "The distribution, ontogeny and origin in the rat of Ia-positive cells with dendritic morphology and of Ia antigen in epithelia, with special reference to the intestine." in: European journal of immunology, Vol. 13, Issue 2, pp. 112-22, (1983) (PubMed).
: "Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus." in: European journal of immunology, Vol. 12, Issue 3, pp. 237-43, (1982) (PubMed).
: "Identification of Ia glycoproteins in rat thymus and purification from rat spleen." in: European journal of immunology, Vol. 9, Issue 6, pp. 426-33, (1980) (PubMed).
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: "Costimulatory molecules CD80 and CD86 in the rat; tissue distribution and expression by antigen-presenting cells." in: Journal of leukocyte biology, Vol. 64, Issue 6, pp. 803-9, (1998) (PubMed).
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- Target
- RT1-BB (RT1 Class II, Locus Bb (RT1-BB))
- Alternative Name
- RT1B (RT1-BB Products)
- Synonyms
- RT1.B antibody, RT1 class II, locus Bb antibody, RT1-Bb antibody
- Pathways
- Production of Molecular Mediator of Immune Response
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