Follicular Dendritic Cells antibody

Catalog No. ABIN2689507

Product Details anti-Follicular Dendritic Cells Antibody

Target: Follicular Dendritic Cells

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Follicular Dendritic Cells antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Brand: BD Pharmingen™

Characteristics: Follicular Dendritic Cells (FDC) form a structural network within the lymphoid follicles and are involved in antigen presentation to B cells for generating an immune response and for the maintenance of immunological memory. FDCs are believed to provide signals to B cells to induce their proliferation. In LCMV mediated immunosuppression there is evidence of T-cell dependent destruction of macrophages and follicular dendritic cells. The FDC-M1 antibody recognizes follicular dendritic cells and their dendritic processes. Immunohistochemistry of follicular dendritic cells. Frozen sections of mouse spleen was reacted with the FDC-M1 antibody. Follicular dendritic cells can be identified by the intense brown labeling of their cell membranes. Magnification 20X.

BD Pharmingen™ Purified Rat Anti-Mouse Follicular Dendritic Cell - Purified - Clone FDC-M1 - Isotype Rat IgG2c, κ - Reactivity Ms - 1 mL

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: FDC

Isotype: IgG2c kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-Follicular Dendritic Cells antibody (ABIN2689507)

Kosco, Pflugfelder, Gray: "Follicular dendritic cell-dependent adhesion and proliferation of B cells in vitro." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 8, pp. 2331-9, (1992) (PubMed).

Gray, Kosco, Stockinger: "Novel pathways of antigen presentation for the maintenance of memory." in: International immunology, Vol. 3, Issue 2, pp. 141-8, (1991) (PubMed).

Target Details for Follicular Dendritic Cells

Target: Follicular Dendritic Cells

Alternative Name: Follicular Dendritic Cell