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- Target See all CD9 Antibodies
- CD9
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD9 antibody is conjugated to Biotin
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Application
- Flow Cytometry (FACS)
- Brand
- BD Pharmingen™
- Characteristics
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The KMC8 antibody reacts with CD9, a 24- kDa member of the transmembrane 4 superfamily. In the mouse, CD9 is present on bone marrow myeloid cells, stromal cells, and megakaryocyte-committed progenitors, subsets of peripheral T and B lymphocytes, and neutrophils, platelets, dendritic cells, and bone marrow-derived macrophages. CD9 has been found to be associated with integrins and other cell-surface receptors, and it is suggested to play a role in signal transduction and possibly in regulating cellular adhesive properties. It has also been demonstrated to participate in T-cell costimulation and induction of apoptosis. The KMC8 antibody has been reported to block certain CD9 functions and activate macrophages
BD Pharmingen™ Biotin Rat Anti-Mouse CD9 - Biotin - Clone KMC8 (also known as KMC 8) - Isotype Rat IgG2a, κ - Reactivity Ms - 0.1 mg - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Immunogen
- (C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal cell line BMS2
- Clone
- KMC8
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CD9 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 4°C.
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Characterization of mouse clonogenic megakaryocyte progenitors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 1, pp. 205-10, (2003) (PubMed).
: "Functional association of CD9 with the Fc gamma receptors in macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 5, pp. 3256-65, (2001) (PubMed).
: "CD9 molecule expressed on stromal cells is involved in osteoclastogenesis." in: Experimental hematology, Vol. 27, Issue 5, pp. 853-9, (1999) (PubMed).
: "Differential involvement of a Fas-CPP32-like protease pathway in apoptosis of TCR/CD9-costimulated, naive T cells and TCR-restimulated, activated T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 12, pp. 5790-6, (1998) (PubMed).
: "Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 5, pp. 2222-31, (1997) (PubMed).
: "Antibody ligation of CD9 modifies production of myeloid cells in long-term cultures." in: Blood, Vol. 87, Issue 6, pp. 2252-61, (1996) (PubMed).
: "The ins and outs of the transmembrane 4 superfamily." in: Immunology today, Vol. 15, Issue 12, pp. 588-94, (1995) (PubMed).
: "Platelet p24/CD9, a member of the tetraspanin family of proteins." in: Annals of the New York Academy of Sciences, Vol. 714, pp. 175-84, (1994) (PubMed).
: "Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures." in: The Journal of experimental medicine, Vol. 171, Issue 2, pp. 477-88, (1990) (PubMed).
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Characterization of mouse clonogenic megakaryocyte progenitors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 1, pp. 205-10, (2003) (PubMed).
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- Target
- CD9
- Alternative Name
- CD9 (CD9 Products)
- Synonyms
- BTCC-1 antibody, DRAP-27 antibody, MIC3 antibody, MRP-1 antibody, TSPAN-29 antibody, TSPAN29 antibody, Tspan29 antibody, cd9 antibody, wu:fb61g04 antibody, zgc:73383 antibody, zgc:85743 antibody, CD9 molecule antibody, CD9 antigen antibody, CD9 molecule a antibody, CD9 antibody, Cd9 antibody, cd9a antibody
- Pathways
- Response to Water Deprivation, Cell-Cell Junction Organization
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