Reacts with several glycosylphosphatidylinositol-anchored glycoproteins present on granulocytes and epithelial cells. Antibody B1.1 was studied as recognizing CD66a, c, d and e in the VI Human Leukocyte Differentiation Workshop. CD66 antigens, also known as the carcinoembryonic antigen (CEA) family of molecules, are closely related to the immunoglobulin superfamily of glycoproteins. Studies on CD66 Molecules suggest a potential adhesion function in vivo. These molecules exhibit both homophilic and heterophilic ashesion. CEA family members may be involved in transmembrane signalling and activation of neutrophils. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood granulocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store undiluted at 4°C.
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