This IL2 Receptor beta antibody is conjugated to Biotin
Application
Flow Cytometry (FACS)
Brand
BD Pharmingen™
Characteristics
The Mik-β3 clone reacts with CD122, the p75 (β chain) of the human high affinity receptor for interleukin 2 (IL-2Rβ), a 70-75 kD type I transmembrane protein expressed on mature T- and pre-B-cell subsets, thymocytes, monocytes, hematopoietic progenitor cells, fetal liver cells and stromal cells. The IL-2Rβ plays a role in B-cell proliferation, T-cell proliferation and activation. Profile of peripheral blood lymphocytes analyzed on a FACScan
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
Storage
4 °C
Storage Comment
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Ishikawa, Uchiyama, Kamio, Onishi, Kodaka, Okuma: "IL-4 down-regulates IL-2 receptor p75 by accelerating its endocytosis." in: International immunology, Vol. 3, Issue 6, pp. 517-25, (1991) (PubMed).
Tsudo, Kitamura, Miyasaka: "Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 6, pp. 1982-6, (1989) (PubMed).
Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).