Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Basophils antibody

Reactivity: Human FACS Host: Mouse Monoclonal Bsp unconjugated
Catalog No. ABIN2688848
  • Target
    Basophils
    Reactivity
    Human
    Host
    • 1
    Mouse
    Clonality
    • 1
    Monoclonal
    Conjugate
    • 1
    This Basophils antibody is un-conjugated
    Application
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Brand
    BD Pharmingen™
    Characteristics
    Bsp-1 reacts with a 45 kDa surface antigen on the human erythroleukemic (HEL) cell line, the KU812 basophilic cell line, and peripheral blood basophils, but not on neutrophils or eosinophils. Bsp-1+ basophils also express CD11 and CD13, but lack lymphoid and other granulocytic/monocytic cell surface antigens. However, they express CD45 and HLA-ABC antigens. In peripheral blood, Bsp-1 reacts with a subset of the CD123+/HLA-DR- population. Bsp-1 is a useful tool in the study of basophil function and differentiation. Profile of anti-Basophil (Bsp-1) on HEL cells analyzed by flow cytometry. Second step staining with Cat. No. 555988.

    BD Pharmingen™ Purified Mouse Anti-Human Basophils - Purified - Clone Bsp-1 - Isotype Mouse IgM, κ - Reactivity Hu - 0.1 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Clone
    Bsp
    Isotype
    IgM kappa
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C.
  • Bodger, Morris, Kennedy, Bowen, Hilton, Fitzgerald: "Basophils (Bsp-1+) derive from the leukemic clone in human myeloid leukemias involving the chromosome breakpoint 9q34." in: Blood, Vol. 73, Issue 3, pp. 777-81, (1989) (PubMed).

    Bodger, Mounsey, Nelson, Fitzgerald: "A monoclonal antibody reacting with human basophils." in: Blood, Vol. 69, Issue 5, pp. 1414-8, (1987) (PubMed).

  • Target
    Basophils
You are here:
Support