TIE1 antibody (AA 385-607)
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- Target See all TIE1 Antibodies
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
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Binding Specificity
- AA 385-607
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TIE1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. coli.
- Clone
- 8D12D2
- Isotype
- IgG1
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
- Alternative Name
- TIE1 (TIE1 Products)
- Synonyms
- JTK14 antibody, TIE antibody, D430008P04Rik antibody, tie-1 antibody, tyrosine kinase with immunoglobulin like and EGF like domains 1 antibody, tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antibody, tyrosine-protein kinase receptor Tie-1 antibody, endothelium-specific receptor tyrosine kinase 1 antibody, TIE1 antibody, Tie1 antibody, CpipJ_CPIJ018933 antibody, tie1 antibody
- Background
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Description: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. ,
Aliases: TIE, JTK14
- Molecular Weight
- 125 kDa
- Gene ID
- 7075
- HGNC
- 7075
- Pathways
- RTK Signaling
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