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TIE1 antibody (AA 385-607)

TIE1 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 8D12D2 unconjugated
Catalog No. ABIN2683015
  • Target See all TIE1 Antibodies
    TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
    Binding Specificity
    • 15
    • 9
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 385-607
    Reactivity
    • 90
    • 38
    • 33
    • 1
    Human
    Host
    • 73
    • 19
    • 1
    Mouse
    Clonality
    • 74
    • 19
    Monoclonal
    Conjugate
    • 40
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIE1 antibody is un-conjugated
    Application
    • 71
    • 41
    • 16
    • 13
    • 13
    • 9
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. coli.
    Clone
    8D12D2
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
    Alternative Name
    TIE1 (TIE1 Products)
    Synonyms
    JTK14 antibody, TIE antibody, D430008P04Rik antibody, tie-1 antibody, tyrosine kinase with immunoglobulin like and EGF like domains 1 antibody, tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antibody, tyrosine-protein kinase receptor Tie-1 antibody, endothelium-specific receptor tyrosine kinase 1 antibody, TIE1 antibody, Tie1 antibody, CpipJ_CPIJ018933 antibody, tie1 antibody
    Background

    Description: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. ,

    Aliases: TIE, JTK14

    Molecular Weight
    125 kDa
    Gene ID
    7075
    HGNC
    7075
    Pathways
    RTK Signaling
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