Menin antibody (AA 392-554)
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- Target See all Menin (MEN1) Antibodies
- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
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Binding Specificity
- AA 392-554
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Menin antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purpose
- MEN1 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human MEN1 (AA: 392-554) expressed in E. Coli.
- Clone
- 7D3E10
- Isotype
- IgG1
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
- Alternative Name
- MEN1 (MEN1 Products)
- Synonyms
- MEAI antibody, SCG2 antibody, menin antibody, meai antibody, scg2 antibody, AW045611 antibody, menin 1 antibody, menin 1 L homeolog antibody, multiple endocrine neoplasia I antibody, multiple endocrine neoplasia 1 antibody, MEN1 antibody, men1 antibody, men1.L antibody, Men1 antibody
- Background
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Description: This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.
Aliases: MEAI, SCG2
- Molecular Weight
- 68kDa
- Gene ID
- 4221
- HGNC
- 4221
- UniProt
- O00255
- Pathways
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
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