Desmoglein 3 antibody (AA 55-159)

Catalog No. ABIN2682987

Product Details anti-Desmoglein 3 Antibody

Target: Desmoglein 3 (DSG3)

Binding Specificity: AA 55-159

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Desmoglein 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: DSG3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human DSG3 (AA: 55-159) expressed in E. Coli.

Clone: 6G2C11

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Desmoglein 3

Target: Desmoglein 3 (DSG3)

Alternative Name: DSG3 (DSG3 Products)

Synonyms: DSG3 antibody, CDHF6 antibody, PVA antibody, bal antibody, balding antibody, desmoglein 3 antibody, DSG3 antibody, Dsg3 antibody

Background:

Description: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Aliases: PVA, CDHF6

Molecular Weight: 107.5kDa

Gene ID: 1830

HGNC: 1830

UniProt: P32926