BACE1 antibody (AA 112-324)
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- Target See all BACE1 Antibodies
- BACE1 (Beta-secretase 1 (BACE1))
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Binding Specificity
- AA 112-324
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BACE1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purpose
- BACE1 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli.
- Clone
- 3C1C3
- Isotype
- IgG1
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- BACE1 (Beta-secretase 1 (BACE1))
- Alternative Name
- BACE1 (BACE1 Products)
- Synonyms
- ASP2 antibody, BACE antibody, HSPC104 antibody, C76936 antibody, Bace antibody, MGC145931 antibody, BACE1 antibody, zgc:77409 antibody, beta-secretase 1 antibody, beta-site APP cleaving enzyme 1 antibody, beta-site APP-cleaving enzyme 1 antibody, BACE1 antibody, Bace1 antibody, bace1 antibody
- Background
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Description: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
Aliases: ASP2, BACE, HSPC104
- Molecular Weight
- 55.7kDa
- Gene ID
- 23621
- HGNC
- 23621
- UniProt
- P56817
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