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BACE1 antibody (AA 112-324)

BACE1 Reactivity: Human WB, ELISA, ICC, FACS Host: Mouse Monoclonal 3C1C3 unconjugated
Catalog No. ABIN2682977
  • Target See all BACE1 Antibodies
    BACE1 (Beta-secretase 1 (BACE1))
    Binding Specificity
    • 16
    • 13
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 112-324
    Reactivity
    • 80
    • 50
    • 40
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 74
    • 9
    • 1
    Mouse
    Clonality
    • 72
    • 12
    Monoclonal
    Conjugate
    • 53
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BACE1 antibody is un-conjugated
    Application
    • 62
    • 34
    • 29
    • 16
    • 13
    • 13
    • 13
    • 10
    • 9
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purpose
    BACE1 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli.
    Clone
    3C1C3
    Isotype
    IgG1
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    BACE1 (Beta-secretase 1 (BACE1))
    Alternative Name
    BACE1 (BACE1 Products)
    Synonyms
    ASP2 antibody, BACE antibody, HSPC104 antibody, C76936 antibody, Bace antibody, MGC145931 antibody, BACE1 antibody, zgc:77409 antibody, beta-secretase 1 antibody, beta-site APP cleaving enzyme 1 antibody, beta-site APP-cleaving enzyme 1 antibody, BACE1 antibody, Bace1 antibody, bace1 antibody
    Background

    Description: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.

    Aliases: ASP2, BACE, HSPC104

    Molecular Weight
    55.7kDa
    Gene ID
    23621
    HGNC
    23621
    UniProt
    P56817
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