HIV-1 p31 antibody (N-Term)

Catalog No. ABIN2669394

Product Details anti-HIV-1 p31 Antibody

Target: HIV-1 p31 (Human Immunodeficiency Virus 1 Integrase (HIV-1 p31))

Binding Specificity: N-Term

Reactivity: Human Immunodeficiency Virus (HIV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This HIV-1 p31 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Characteristics: Integration of viral DNA into a chromosome of the host cell is an essential step in the retroviral life cycle. This process is catalyzed by the viral enzyme integrase (IN) through 3 steps: first step, two nucleotides are removed from the 39 ends of the viral DNA (39-end processing), second step, the recessed 39 ends of the viral DNA are then joined to 59 staggered sites in the target DNA in a concerted cleavage and ligation reaction (DNA joining), last step, integration is completed by repair of the short gaps flanking the viral DNA intermediate and subsequent joining of the 59 ends of viral DNA to the target DNA.

Purification: Antibodies are purified from supernatants of hybridoma cell cultures by affinity chromatography.

Immunogen: Bacterially expressed, hexahistidine amino-terminal tagged HIV-1 integrase protein (clade B, HXB-3 isolate)

Clone: 2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol

Storage: 4 °C

Target Details for HIV-1 p31

Target: HIV-1 p31 (Human Immunodeficiency Virus 1 Integrase (HIV-1 p31))

Alternative Name: Integrase HIV1 (HIV-1 p31 Products)

Target Type: Viral Protein