WHSC1 antibody (AA 1-647)

Catalog No. ABIN2668917

Product Details anti-WHSC1 Antibody

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Binding Specificity: AA 1-647

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This WHSC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC)

Purification: Protein G Chromatography

Immunogen: This MMSET / WHSC1 antibody was raised against a recombinant protein corresponding to amino acids 1-647 of human MMSET-I.

Clone: 29D1

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-WHSC1 antibody (ABIN2668917)

García-Carpizo, Sarmentero, Han, Graña, Ruiz-Llorente, Pisano, Serrano, Brooks, Campbell, Barrero: "NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation." in: Scientific reports, Vol. 6, pp. 32952, (2016) (PubMed).

Marango, Shimoyama, Nishio, Meyer, Min, Sirulnik, Martinez-Martinez, Chesi, Bergsagel, Zhou, Waxman, Leibovitch, Walsh, Licht: "The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor." in: Blood, Vol. 111, Issue 6, pp. 3145-54, (2008) (PubMed).

Target Details for WHSC1

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Alternative Name: MMSET / WHSC1 (WHSC1 Products)

Molecular Weight: 88 & 157 kDa

Gene ID: 7468

Pathways: SARS-CoV-2 Protein Interactome