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IRF5 antibody
IRF5
Reactivity: Human
BCA
Host: Mouse
Monoclonal
11F4A09
unconjugated
Product Details anti-IRF5 Antibody
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Target
See all IRF5 Antibodies
IRF5
(Interferon Regulatory Factor 5 (IRF5))
Reactivity
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Human
Host
All hosts for IRF5 antibodies
Mouse
Clonality
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Monoclonal
Conjugate
All conjugates for IRF5 antibodies
This IRF5 antibody is un-conjugated
Application
All applications for IRF5 antibodies
Biochemical Assay (BCA)
Clone
11F4A09
Isotype
IgG2b kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
phosphate-buffered solution, pH 7.2, containing 0.05 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Upon receipt, store undiluted between 2°C and 8°C.
Target Details for IRF5
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Target
IRF5
(Interferon Regulatory Factor 5 (IRF5))
Alternative Name
IRF5 (IRF5 Products )
Synonyms
IRF5 antibody, irf5 antibody, SLEB10 antibody, AW491843 antibody, mirf5 antibody, im:7155364 antibody, zgc:76986 antibody, interferon regulatory factor 5 antibody, interferon regulatory factor 5 L homeolog antibody, IRF5 antibody, irf5 antibody, Irf5 antibody, irf5.L antibody
Background
IRF-5 is a transcription factor belonging to the interferon regulatory factor family. It controls induction of type I IFN genes as well as inflammatory cytokines and chemokines through TLRs and the MyD88-TRAF6 pathway. Several genetic variations of IRF-5 have been reported as a risk factor of Systemic lupus erythematosus (SLE), which is caused by excess IFNα induction.
Pathways
TLR Signaling , Autophagy
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