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IRF9 antibody

IRF9 Reactivity: Human FACS Host: Mouse Monoclonal 5A3A39 unconjugated
Catalog No. ABIN2666230
  • Target See all IRF9 Antibodies
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Reactivity
    • 47
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 6
    • 1
    Mouse
    Clonality
    • 44
    • 4
    Monoclonal
    Conjugate
    • 24
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRF9 antibody is un-conjugated
    Application
    • 36
    • 15
    • 13
    • 13
    • 10
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    Flow Cytometry (FACS)
    Purification
    Affinity purified.
    Clone
    5A3A39
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product IRF9 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Upon receipt, store undiluted 2°C and 8°C.
  • Target
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Alternative Name
    IRF9 (IRF9 Products)
    Synonyms
    IRF-9 antibody, ISGF3 antibody, ISGF3G antibody, p48 antibody, zgc:92097 antibody, Irf-9 antibody, Isgf3g antibody, interferon regulatory factor 9 antibody, IRF9 antibody, irf9 antibody, Irf9 antibody
    Background
    IRF9 is a member of the IRF family of transcription factors and plays an important role in IFN signaling pathways and anti-viral immune responses. Type I and type III interferon stimulation induces phosphorylation and heterodimerization of STAT1 and STAT2. The activated STAT1:STAT2 heterodimer recruits IRF9 and forms a heterotrimeric complex termed IFN-stimulated gene factor 3 (ISGF3). The ISGF3 complex, in turn, translocates to the nucleus and transactivates IFN-inducible genes. The IRF9 protein in the ISGF3 complex is responsible for the recognition of IFN-stimulated response elements (ISRE). Mice lacking IRF9 fail to induce the expression of IFN regulated genes in response to type I interferon stimulation, indicating that IRF9 is crucial in mediating interferon signaling.
    Pathways
    JAK-STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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