SUPT16H antibody

Catalog No. ABIN2666085

Product Details anti-SUPT16H Antibody

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SUPT16H antibody is un-conjugated

Application: Biochemical Assay (BCA)

Cross-Reactivity (Details): weakly reacts with mouse Spt16

Purification: The antibody was purified by affinity chromatography.

Clone: 8D2

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide. The antibody is provided at 0.5 mg/mL.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Upon receipt, store between 2°C and 8°C.

Target Details for SUPT16H

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Alternative Name: Spt16 (SUPT16H Products)

Background: Spt16 is a 120-140 kD nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT140 complex is composed of the Spt16 and the SSRP1 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. The 8D2 monoclonal antibody recognizes human Spt16 and has been shown to be useful for Western blotting.

Pathways: Chromatin Binding