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FLT4 antibody

FLT4 Reactivity: Human FACS Host: Mouse Monoclonal 9D9F9 unconjugated
Catalog No. ABIN2665454
  • Target See all FLT4 Antibodies
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    Reactivity
    • 81
    • 49
    • 16
    • 11
    Human
    Host
    • 72
    • 24
    • 8
    • 2
    Mouse
    Clonality
    • 73
    • 33
    Monoclonal
    Conjugate
    • 56
    • 11
    • 7
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLT4 antibody is un-conjugated
    Application
    • 57
    • 43
    • 37
    • 27
    • 14
    • 13
    • 13
    • 10
    • 8
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    9D9F9
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product FLT4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    Alternative Name
    VEGFR-3 (FLT4 Products)
    Synonyms
    FLT41 antibody, LMPH1A antibody, PCL antibody, VEGFR3 antibody, AI323512 antibody, Chy antibody, Flt-4 antibody, VEGFR-3 antibody, Vegfr3 antibody, cb1059 antibody, fms related tyrosine kinase 4 antibody, FMS-like tyrosine kinase 4 antibody, fms-related tyrosine kinase 4 antibody, FLT4 antibody, Flt4 antibody, flt4 antibody
    Background
    Receptor tyrosine Kinase VEGFR-3, also known as FLT4, together with VEGFR1 (FIT1) and VEGFR2 (KDR/Flk-1), are the receptors for vascular endothelial growth factors (VEGF). The VEGFR family belongs to the class II subfamily of receptor tyrosine kinases (RTKs), containing a large extracellular region which is composed of seven Ig-like domains (D1-D7), a single transmembrane, helix, and a cytoplasmic region with tyrosine kinase activity. In VEGFR-3, the fifth Ig homology domain is proteolytically cleaved which results in polypeptides that remain linked by two disulfide bonds. VEGFR-3 is widely expressed on all endothelial cells in early embryogenesis, while, in adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. VEGF-C and VEGF-D activation of VEGFR-3 plays an important role in the formation of the lymphatic vessel system. Aberrant activation or expression of VEGFR and their ligands has been implicated in tumor angiogenesis, coronary artery disease, diabetic blindness, and other diseases.
    Pathways
    RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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