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Sema4a antibody
Sema4a
Reactivity: Human, Mouse
WB, IHC, IP, ELISA (Capture), ELISPOT (Detection), ICFC, Neut
Host: Mouse
Monoclonal
5E3-SEMA4A
unconjugated
Product Details anti-Sema4a Antibody
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Target
See all Sema4a Antibodies
Sema4a
(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a))
Reactivity
All reactivities for Sema4a antibodies
Human, Mouse
Host
All hosts for Sema4a antibodies
Mouse
Clonality
All clonalities for Sema4a antibodies
Monoclonal
Conjugate
All conjugates for Sema4a antibodies
This Sema4a antibody is un-conjugated
Application
All applications for Sema4a antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA (Capture), ELISpot (Detection) (ELISPOT (Detection)), Intracellular Flow Cytometry (ICFC), Neutralization (Neut)
Purification
The antibody was purified by affinity chromatography.
Clone
5E3-SEMA4A
Isotype
IgG1 lambda
Top Product
Discover our top product Sema4a Primary Antibody
Alternatives
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anti-Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a) (AA 361-460) antibody
Sema4a
Reactivity: Human, Mouse
WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for Sema4a
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Target
Sema4a
(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a))
Alternative Name
SEMA4A (Sema4a Products )
Synonyms
SEMA4A antibody, CORD10 antibody, RP35 antibody, SEMAB antibody, SEMB antibody, AI132332 antibody, SemB antibody, Semab antibody, semaphorin 4A antibody, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A antibody, SEMA4A antibody, sema4a antibody, Sema4a antibody
Background
Semaphorin 4A (SEMA4A) is a class IV semaphorin of soluble and transmembrane proteins originally identified as SemB. It is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain, and a Sema domain. SEMA4A is expressed on dendritic cells, activated B cells, and T cells. It is also found on different tissues, such as those in brain, lung, kindney, spleen, and testis. In the immune system, SEMA4A functions as an activator in the T-cell-mediated immune response and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Like other semaphorin family members it is also involved in guidance of axonal migration during neuronal development and in immune responses.
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