PRC1 antibody

Catalog No. ABIN2665339

Product Details anti-PRC1 Antibody

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PRC1 antibody is un-conjugated

Application: Biochemical Assay (BCA)

Purification: The antibody was purified by affinity chromatography.

Clone: 6G2

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for PRC1

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Alternative Name: PRC1 (PRC1 Products)

Synonyms: cb212 antibody, prc1 antibody, prc1l antibody, zgc:55982 antibody, zgc:86918 antibody, MGC68845 antibody, zgc:55664 antibody, ase1 antibody, ASE1 antibody, D7Ertd348e antibody, protein regulator of cytokinesis 1 antibody, protein regulator of cytokinesis 1a antibody, protein regulator of cytokinesis 1 S homeolog antibody, protein regulator of cytokinesis 1b antibody, PRC1 antibody, prc1a antibody, prc1.S antibody, prc1b antibody, CNC07120 antibody, prc1 antibody, Prc1 antibody

Background: PRC1 (also known as protein regulator of cytokinesis 1 and mitotic spindle-associated CDK substrate) is a member of the MAP65/ASE1 family with a molecular weight of approximately 72 kD. PRC1 localization changes with cell-cycle position and can be found in the nucleus, the mitotic spindle, and the cell mid-body. PRC1 is a mitotic spindle-associated CDK substrate protein required for cytokinesis and maintenance of the spindle midzone. PRC1 can be modified by phosphorylation and has been shown to interact with Cdc2 and Cdk2. The 6G2 antibody recognizes the human PRC1 protein and has been shown to be useful for Western blotting.