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IL-4 antibody
IL4
Reactivity: Human
BCA
Host: Mouse
Monoclonal
8D4-8
unconjugated
Product Details anti-IL-4 Antibody
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Target
See all IL-4 (IL4) Antibodies
IL-4 (IL4)
(Interleukin 4 (IL4))
Reactivity
All reactivities for IL-4 antibodies
Human
Host
All hosts for IL-4 antibodies
Mouse
Clonality
All clonalities for IL-4 antibodies
Monoclonal
Conjugate
All conjugates for IL-4 antibodies
This IL-4 antibody is un-conjugated
Application
All applications for IL-4 antibodies
Biochemical Assay (BCA)
Cross-Reactivity
Chimpanzee, Cynomolgus, Rhesus Monkey, Baboon
Purification
The antibody was purified by affinity chromatography.
Clone
8D4-8
Isotype
IgG1 kappa
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Discover our top product IL4 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for IL-4
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Target
IL-4 (IL4)
(Interleukin 4 (IL4))
Alternative Name
IL-4 (IL4 Products )
Synonyms
IL4 antibody, IL-4 antibody, BCGF-1 antibody, BCGF1 antibody, BSF-1 antibody, BSF1 antibody, Il-4 antibody, Il4e12 antibody, IL2 antibody, interleukin 4 antibody, IL4 antibody, Il4 antibody
Background
IL-4 is a pleiotropic cytokine that is produced by activated T cells mast cells and basophils. IL-4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10 and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells. The 8D4-8 antibody can neutralize the bioactivity of natural or recombinant IL-4.
Pathways
JAK-STAT Signaling , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Proton Transport , Activated T Cell Proliferation
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