FPR3 antibody

Catalog No. ABIN2664985

Product Details anti-FPR3 Antibody

Target: FPR3 (Formyl Peptide Receptor 3 (FPR3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FPR3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Intracellular Flow Cytometry (ICFC), Cytometry by Time of Flight (CyTOF)

Purification: The antibody was purified by affinity chromatography.

Clone: K102B9

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for FPR3

Target: FPR3 (Formyl Peptide Receptor 3 (FPR3))

Alternative Name: FPR3 (FPR3 Products)

Synonyms: RGD1566044 antibody, FML2_HUMAN antibody, FMLPY antibody, FPRH1 antibody, FPRH2 antibody, FPRL2 antibody, RMLP-R-I antibody, ALX antibody, Fpr-rs1 antibody, Fpr-s1 antibody, Fprl1 antibody, LXA4-R antibody, Lxa4r antibody, FMLP-R-II antibody, formyl peptide receptor 3 antibody, Fpr3 antibody, FPR3 antibody

Background: FPR3, also known as FPRL2, belongs to the formyl peptide receptor family which includes FPR1, FPR2, and FPR3. Monocytes express FPR1, 2, and 3, upon differentiation into macrophages, expression of these receptors is maintained. Two ligands, humanin and F2L have been identified. Humanin is expressed in the heart, skeletal muscle, kidney, and liver but is not expressed in the immune system. F2L is a heme-binding protein first identified in the spleen. Binding of FPRL2 and F2L induces Ca2+ mobilization and neutrophil chemotaxis. Low level of expression of FPRL2 has also been reported on NK cells.