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CD3 epsilon antibody
CD3E
Reactivity: Human, Mouse
FACS
Host: Mouse
Monoclonal
APA1-1
unconjugated
Product Details anti-CD3 epsilon Antibody
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Target
See all CD3 epsilon (CD3E) Antibodies
CD3 epsilon (CD3E)
Reactivity
All reactivities for CD3 epsilon antibodies
Human, Mouse
Host
All hosts for CD3 epsilon antibodies
Mouse
Clonality
All clonalities for CD3 epsilon antibodies
Monoclonal
Conjugate
All conjugates for CD3 epsilon antibodies
This CD3 epsilon antibody is un-conjugated
Application
All applications for CD3 epsilon antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
APA1-1
Isotype
IgG1 kappa
Top Product
Discover our top product CD3E Primary Antibody
Alternatives
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anti-CD3 epsilon (CD3E) (AA 156-168), (Cytoplasmic Domain) antibody
CD3E
Reactivity: Human, Rat, Pig, Rabbit, Cow, Horse, Guinea Pig, Chicken
FACS, WB, IF
Host: Mouse
Monoclonal
PC3-188A
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CD3 epsilon
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Target
CD3 epsilon (CD3E)
Alternative Name
CD3epsilon (CD3E Products )
Synonyms
cd3e antibody, CD3E antibody, t3e antibody, tcre antibody, AI504783 antibody, CD3 antibody, CD3epsilon antibody, T3e antibody, T3E antibody, TCRE antibody, CD3e molecule antibody, CD3 antigen, epsilon polypeptide antibody, cd3e antibody, CD3E antibody, Cd3e antibody
Background
The CD3ε chain of the CD3-TCR complex is a type I membrane protein that undergoes conformational change following ligation of the TCR-CD3 complex. This conformational change leads to exposure of the proline rich sequence in CD3ε and results in recruitment of Nck. It is expressed by all mature T cells and forms a heteromeric complex with CD3 α/β or γ/ δ and ζ chains. It is important in T cell development, and deficiency of this gene has been associated with severe immunodeficiency.
Pathways
TCR Signaling , CXCR4-mediated Signaling Events , Ubiquitin Proteasome Pathway
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