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Macrophage Mannose Receptor 1 antibody
MRC1
Reactivity: Human
MA
Host: Mouse
Monoclonal
15-2
unconjugated
Product Details anti-Macrophage Mannose Receptor 1 Antibody
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Target
See all Macrophage Mannose Receptor 1 (MRC1) Antibodies
Macrophage Mannose Receptor 1 (MRC1)
(Mannose Receptor, C Type 1 (MRC1))
Reactivity
All reactivities for Macrophage Mannose Receptor 1 antibodies
Human
Host
All hosts for Macrophage Mannose Receptor 1 antibodies
Mouse
Clonality
All clonalities for Macrophage Mannose Receptor 1 antibodies
Monoclonal
Conjugate
All conjugates for Macrophage Mannose Receptor 1 antibodies
This Macrophage Mannose Receptor 1 antibody is un-conjugated
Application
All applications for Macrophage Mannose Receptor 1 antibodies
Multiplex Assay (MA)
Purification
The antibody was purified by affinity chromatography.
Clone
15-2
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for Macrophage Mannose Receptor 1
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Target
Macrophage Mannose Receptor 1 (MRC1)
(Mannose Receptor, C Type 1 (MRC1))
Alternative Name
CD206 (MRC1 Products )
Synonyms
CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mrc1 antibody, MGC86525 antibody, MRC1 antibody, MRC1L-A antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, mannose receptor C-type 1 L homeolog antibody, mediator of replication checkpoint 1 antibody, MRC1 antibody, Mrc1 antibody, mrc1.L antibody, mrc1 antibody
Background
Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.
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