CCR9 antibody

Catalog No. ABIN2664347

Product Details anti-CCR9 Antibody

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCR9 antibody is un-conjugated

Application: Intracellular Flow Cytometry (ICFC)

Purification: The antibody was purified by affinity chromatography.

Clone: L053E8

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CCR9

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Alternative Name: CD199 (CCR9 Products)

Background: Human CD199, also known as CCR9, is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in the gut-associated immune response. It is highly expressed on different stages of thymocytes and upregulated on CD4+ CD8+ cells. Expression of CCR9 on γ/δ T cells in the intraepithelial and small intestine has been reported. The interaction of CCR9 with its ligand CCL25 (TECK, thymus-expressed chemokine) may direct the trafficking of developing T cells in the thymus and the generation of gut-specific immunological memory.