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VPREB1 antibody
VPREB1
Reactivity: Mouse
ICFC
Host: Rat
Monoclonal
R3
unconjugated
Product Details anti-VPREB1 Antibody
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Target
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VPREB1
(Pre-B Lymphocyte 1 (VPREB1))
Reactivity
All reactivities for VPREB1 antibodies
Mouse
Host
All hosts for VPREB1 antibodies
Rat
Clonality
All clonalities for VPREB1 antibodies
Monoclonal
Conjugate
All conjugates for VPREB1 antibodies
This VPREB1 antibody is un-conjugated
Application
All applications for VPREB1 antibodies
Intracellular Flow Cytometry (ICFC)
Purification
The antibody was purified by affinity chromatography.
Clone
R3
Isotype
IgG2a kappa
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Discover our top product VPREB1 Primary Antibody
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for VPREB1
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Target
VPREB1
(Pre-B Lymphocyte 1 (VPREB1))
Alternative Name
CD179a (VPREB1 Products )
Synonyms
IGI antibody, IGVPB antibody, VPREB antibody, VpreB antibody, CD179a antibody, Vpreb-1 antibody, V-set pre-B cell surrogate light chain 1 antibody, immunoglobulin iota chain antibody, immunoglobulin iota chain-like antibody, pre-B lymphocyte 1 antibody, pre-B lymphocyte gene 1 antibody, VPREB1 antibody, LOC698810 antibody, LOC486411 antibody, Vpreb1 antibody
Background
CD179a, also known as VpreB, is an 18 kD member of the Ig superfamily, with an Ig V-like domain structure (that lacks the β strand of a typical V domain). CD179a associates with CD179b to form a surrogate light (SL) chain, which associates with the IgM heavy chain and the CD79a/CD79b heterodimer to form the pre-B cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation, though it has been reported that deficiency of CD179a and/or CD179b impairs the maturation of the B cell precursors beyond the pre-B cell stage.
Pathways
Production of Molecular Mediator of Immune Response , Regulation of Cell Size
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