Fc Receptor, IgG, Low Affinity IV (FCGR4) antibody

Catalog No. ABIN2664272

Product Details

Target: Fc Receptor, IgG, Low Affinity IV (FCGR4)

Reactivity: Mouse

Host: Armenian Hamster

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography.

Clone: 9E9

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: Fc Receptor, IgG, Low Affinity IV (FCGR4)

Alternative Name: CD16.2 (FCGR4 Products)

Synonyms: 4833442P21Rik antibody, CD16-2 antibody, FcgRIV antibody, FcgammaRIV antibody, Fcgr3a antibody, Fcrl3 antibody, Fc receptor, IgG, low affinity IV antibody, Fcgr4 antibody

Background: FcγRIV, also known as CD16-2, is an intermediate-affinity activating receptor for IgG2a and IgG2b. It is expressed on peripheral blood leukocytes, spleen, thymus, colon, and the intestine. CD16.2 is the mouse homolog of human Fcγ RIIIA. CD16.2 is a low-affinity IgE receptor for all allotypes and the ligation of FcγRIV by antigen-IgE immune complexes promotes macrophage-mediated phagocytosis and is involved in lung inflammation.