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CCR8 antibody
CCR8
Reactivity: Human
IHC, ELISPOT (Capture), ICFC, ELISA (Capture)
Host: Mouse
Monoclonal
L263G8
unconjugated
Product Details anti-CCR8 Antibody
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Target
See all CCR8 Antibodies
CCR8
(Chemokine (C-C Motif) Receptor 8 (CCR8))
Reactivity
All reactivities for CCR8 antibodies
Human
Host
All hosts for CCR8 antibodies
Mouse
Clonality
All clonalities for CCR8 antibodies
Monoclonal
Conjugate
All conjugates for CCR8 antibodies
This CCR8 antibody is un-conjugated
Application
All applications for CCR8 antibodies
Immunohistochemistry (IHC), ELISpot (Capture) (ELISPOT (Capture)), Intracellular Flow Cytometry (ICFC), ELISA (Capture)
Purification
The antibody was purified by affinity chromatography.
Clone
L263G8
Isotype
IgG2a kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CCR8
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Target
CCR8
(Chemokine (C-C Motif) Receptor 8 (CCR8))
Alternative Name
CCR8 (CCR8 Products )
Synonyms
CC-CKR-8 antibody, CCR-8 antibody, CDw198 antibody, CKRL1 antibody, CMKBR8 antibody, CMKBRL2 antibody, CY6 antibody, GPRCY6 antibody, TER1 antibody, C-C antibody, C-C CKR-8 antibody, CKR-8 antibody, Cmkbr8 antibody, mCCR8 antibody, C-C motif chemokine receptor 8 antibody, chemokine (C-C motif) receptor 8 antibody, CCR8 antibody, Ccr8 antibody
Background
CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.
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