CCR10 antibody

Catalog No. ABIN2664100

Product Details anti-CCR10 Antibody

Target: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Reactivity: Human

Host: Armenian Hamster

Clonality: Monoclonal

Conjugate: This CCR10 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Reagent (BR)

Cross-Reactivity: Rhesus Monkey

Purification: The antibody was purified by affinity chromatography.

Clone: 6588-5

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CCR10

Target: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Alternative Name: CCR10 (CCR10 Products)

Synonyms: GPR2 antibody, Cmkbr9 antibody, Gpr2 antibody, zgc:91924 antibody, CCR10 antibody, C-C motif chemokine receptor 10 antibody, chemokine (C-C motif) receptor 10 antibody, CCR10 antibody, Ccr10 antibody, ccr10 antibody

Background: CCR10, also known as GPR-2, is a G-protein-coupled seven transmembrane CC-chemokine receptor. It is the receptor of CCL27 (CTACK/ALP/ILC/ESkine) and CCL28 (MEC) and is expressed on a small subset of T memory cells, IgA-secreting cells, EBV-immortalized B cells, dermal microvascular endothelial cells and dermal fibroblasts. The interaction of CCR10 with its ligands plays a role in the regulation of T cell homing into cutaneous site and IgA-secreting cells migration.