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T-Bet antibody (FITC)

Reactivity: Human, Mouse FACS Host: Mouse Monoclonal 4B10 FITC
Catalog No. ABIN2661995
  • Target See all T-Bet Antibodies
    T-Bet
    Reactivity
    • 61
    • 31
    • 27
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 58
    • 6
    Mouse
    Clonality
    • 58
    • 6
    Monoclonal
    Conjugate
    • 30
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This T-Bet antibody is conjugated to FITC
    Application
    • 53
    • 23
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    Clone
    4B10
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product T-Bet Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    T-Bet
    Abstract
    T-Bet Products
    Synonyms
    T-PET antibody, T-bet antibody, TBET antibody, TBLYM antibody, TBT1 antibody, Tbet antibody, Tblym antibody, T-box 21 antibody, TBX21 antibody, Tbx21 antibody
    Background
    T-bet, also known as T-box transcription factor T-bet, is considered to be a "master regulator" of Th1 lymphoid development controlling the production of the cytokine IFN-γ. T-bet is widely expressed in hematopoietic cells including stem cells, NK cells, B cells, and T cells. T-bet is critical for the control of microbial pathogens, and knockout animals show multiple physiologic and inflammatory features characteristic of asthma. T-bet expression is optimally observed after IL-12 stimulation and can be suppressed by addition of the Th2 cytokine IL-4 or neutralization of IL-12.
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