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CD77 antibody (FITC)

Reactivity: Human FACS, IHC, IP Host: Mouse Monoclonal 5B5 FITC
Catalog No. ABIN2661420
  • Target See all CD77 products
    CD77
    Reactivity
    Human
    Host
    • 6
    Mouse
    Clonality
    • 6
    Monoclonal
    Conjugate
    • 2
    • 2
    • 2
    This CD77 antibody is conjugated to FITC
    Application
    • 6
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Purification
    The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC and unconjugated antibody.
    Clone
    5B5
    Isotype
    IgM kappa
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD77
    Abstract
    CD77 Products
    Background
    CD77, also known as Gb3S, A14GALT, A4GALT1, is a type II membrane protein. It was found specifically expressed on Burkitt's lymphoma cells and on a subset of germinal center B lymphocytes. CD77 has been described as a receptor for Shiga Toxin and Verotoxin 1 (VT1), which is produced by Shigella dysenteriae and some strains of E. coli . It is used as a marker for germinal center stage B-cells. CD19 has been reported as a ligand for D77 and their interaction functions in adhesion and signal transduction at a specific stage of B cell development. Studies have shown that cross-linking CD77 induces apoptosis in some B cell lines.
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