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NCR1 antibody (Biotin)
NCR1
Reactivity: Mouse
ELISA (Detection), ELISPOT (Detection)
Host: Rat
Monoclonal
29A1-4
Biotin
Product Details anti-NCR1 Antibody (Biotin)
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Target
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NCR1
(Natural Cytotoxicity Triggering Receptor 1 (NCR1))
Reactivity
All reactivities for NCR1 antibodies
Mouse
Host
All hosts for NCR1 antibodies
Rat
Clonality
All clonalities for NCR1 antibodies
Monoclonal
Conjugate
All conjugates for NCR1 antibodies
This NCR1 antibody is conjugated to Biotin
Application
All applications for NCR1 antibodies
ELISA (Detection), ELISpot (Detection) (ELISPOT (Detection))
Purification
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Clone
29A1-4
Isotype
IgG2a kappa
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for NCR1
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Target
NCR1
(Natural Cytotoxicity Triggering Receptor 1 (NCR1))
Alternative Name
CD335 (NCR1 Products )
Synonyms
CD335 antibody, LY94 antibody, NK-p46 antibody, NKP46 antibody, Ly94 antibody, NKp46 antibody, KILR-1 antibody, Nk-p46 antibody, Nkp46 antibody, natural cytotoxicity triggering receptor 1 antibody, NCR1 antibody, Ncr1 antibody
Background
CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NK-like T cells, it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.
Pathways
Regulation of Leukocyte Mediated Immunity
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