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CD57 antibody (Biotin)
B3GAT1
Reactivity: Human
IHC, IP, ELISA (Capture), ICFC
Host: Mouse
Monoclonal
HNK-1
Biotin
Product Details anti-CD57 Antibody (Biotin)
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Target
See all CD57 (B3GAT1) Antibodies
CD57 (B3GAT1)
(beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))
Reactivity
All reactivities for CD57 antibodies
Human
Host
All hosts for CD57 antibodies
Mouse
Clonality
All clonalities for CD57 antibodies
Monoclonal
Conjugate
All conjugates for CD57 antibodies
This CD57 antibody is conjugated to Biotin
Application
All applications for CD57 antibodies
Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA (Capture), Intracellular Flow Cytometry (ICFC)
Purification
The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Clone
HNK-1
Isotype
IgM kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CD57
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Target
CD57 (B3GAT1)
(beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))
Alternative Name
CD57 (B3GAT1 Products )
Synonyms
CD57 antibody, GLCATP antibody, GLCUATP antibody, HNK1 antibody, LEU7 antibody, NK-1 antibody, NK1 antibody, 0710007K08Rik antibody, AI846286 antibody, GlcAT-P antibody, Glcatp antibody, Hnk1 antibody, Hnk-1 antibody, b3gat1 antibody, si:dkey-22o20.1 antibody, cd57 antibody, glcatp antibody, glcuatp antibody, hnk-1 antibody, hnk1 antibody, leu7 antibody, nk-1 antibody, nk1 antibody, beta-1,3-glucuronyltransferase 1 antibody, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) antibody, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a antibody, beta-1,3-glucuronyltransferase 1 L homeolog antibody, B3GAT1 antibody, B3gat1 antibody, b3gat1a antibody, b3gat1.L antibody
Background
CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).
Pathways
Glycosaminoglycan Metabolic Process
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