VISTA
(V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))
Reactivity
Mouse
Host
Armenian Hamster
Clonality
Monoclonal
Conjugate
This VISTA antibody is conjugated to PerCP-Cy5.5
Application
Western Blotting (WB), Immunohistochemistry (IHC), ELISA (Capture), Cytometry by Time of Flight (CyTOF)
Purification
The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
PD-1H, also known as VISTA, is a 309 aa type I transmembrane protein, composed of seven exons. PD-1H has one Ig-V like domain, and its sequence is similar to the Ig-V domains of the members of CD28 and B7 families. PD-1H is expressed by a subset of T cells, macrophages, dendritic cells, neutrophils, and NK cells. It has been proposed that PD-1H can be useful to modulate the host immune response to allogeneic transplants.