The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
MGC179455 antibody, CLL-1 antibody, CLL1 antibody, DCAL-2 antibody, MICL antibody, D230024O04 antibody, KLRL1 antibody, Micl antibody, C-type lectin domain family 12 member A antibody, C-type lectin domain family 12, member a antibody, C-type lectin domain family 12, member A antibody, CLEC12A antibody, Clec12a antibody
Background
CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family. Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases. Mouse CLEC12A is expressed on CD8 + dendritic cells (DCs), a proportion of CD8- dendritc cells, plasmacytoid DCs, monoctyes, macrophages, granulocytes, and B cells.