Siglec H antibody (Alexa Fluor 647)

Catalog No. ABIN2658001

Product Details anti-Siglec H Antibody (Alexa Fluor 647)

Target: Siglec H

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Siglec H antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Characteristics: The Siglec-H is a member of CD33-related Siglec family which mostly expressed in the innate immune system. Siglec-H is reported to be specifically expressed on plasmacytoid dendritic cells. Siglec-H depends on adaptor protein DAP 12 (DNAX-activating protein of 12 kD) for surface expression and signal transduction. Cross-linking with this antibody can selectively inhibit interferon-alpha production by IPCs following TLR9 ligation.

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Clone: 551

Isotype: IgG1, IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for Siglec H

Target: Siglec H

Abstract: Siglec H Products

Synonyms: 6430529G09Rik antibody, Siglec-H antibody, sialic acid binding Ig-like lectin H antibody, Siglech antibody