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IL7R antibody (Alexa Fluor 488)
IL7R
Reactivity: Mouse
FACS, ICFC
Host: Rat
Monoclonal
SB-199
Alexa Fluor 488
Product Details anti-IL7R Antibody (Alexa Fluor 488)
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Target
See all IL7R Antibodies
IL7R
(Interleukin 7 Receptor (IL7R))
Reactivity
All reactivities for IL7R antibodies
Mouse
Host
All hosts for IL7R antibodies
Rat
Clonality
All clonalities for IL7R antibodies
Monoclonal
Conjugate
All conjugates for IL7R antibodies
This IL7R antibody is conjugated to Alexa Fluor 488
Application
All applications for IL7R antibodies
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
Clone
SB-199
Isotype
IgG2b kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for IL7R
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Target
IL7R
(Interleukin 7 Receptor (IL7R))
Alternative Name
CD127 (IL7R Products )
Synonyms
IL7R antibody, CD127 antibody, IL-7Ralpha antibody, CDW127 antibody, IL-7R-alpha antibody, IL7RA antibody, ILRA antibody, IL-7RA antibody, interleukin 7 receptor antibody, IL7R antibody, Il7r antibody
Background
CD127 is a 60-90 kD type I transmembrane glycoprotein, also known as IL-7 receptor α chain or IL-7Rα. It forms heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.
Pathways
JAK-STAT Signaling , Regulation of Leukocyte Mediated Immunity , Production of Molecular Mediator of Immune Response , Regulation of Cell Size
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